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Common ADHD Medications: Side Effects & Management Advice

Whether you have recently started ADHD medication or have been taking it for some time, it is important to understand the possible side effects and how they can be managed. Different medications can affect people in different ways, and many common side effects improve during the first few weeks of treatment.
 

This guide explains some of the most frequently reported side effects for commonly prescribed ADHD medications, including Lisdexamfetamine, Dexamfetamine, Methylphenidate, Atomoxetine, and Intuniv (Guanfacine XL). Alongside each side effect, we've included practical management advice to help you understand what is normal, when symptoms may settle naturally, and when you should seek advice from your clinical team.
 

Please remember that this page is intended as general guidance only and should not replace personalised medical advice. If you have concerns about your medication or experience unexpected side effects, please contact Dr J & Colleagues or your healthcare professional for individual support.

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Common Side Effects

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Reduced appetite
Reduced appetite is one of the most common side effects of stimulant ADHD medications. This often improves over time, but eating well remains important during treatment.

Helpful tips
 

  • Eat a substantial breakfast before taking your medication.

  • Choose calorie-dense snacks later in the day if your appetite is reduced.

  • Don't skip meals, even if you don't feel hungry.

  • Stay hydrated throughout the day.

Difficulty Sleeping
Some ADHD medications can make it harder to fall asleep, particularly if they are taken later in the day.

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Helpful tips
 

  • Take your medication as early in the morning as advised.

  • Avoid caffeine during the afternoon and evening.

  • Maintain a consistent bedtime routine.

  • Speak to your clinician if sleep problems continue.

Dry Mouth
Dry mouth is usually mild but can become uncomfortable if left unmanaged.

Helpful tips
 

  • Sip water regularly throughout the day.

  • Chew sugar-free gum to stimulate saliva.

  • Consider sugar-free lozenges if recommended.

  • Maintain good oral hygiene and regular dental check-ups.

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Increased Heart Rate or Blood Pressure
Some ADHD medications may increase your heart rate or blood pressure. This is usually monitored throughout your treatment.

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Helpful tips
 

  • Eat a substantial breakfast before taking your medication.

  • Choose calorie-dense snacks later in the day if your appetite is reduced.

  • Don't skip meals, even if you don't feel hungry.

  • Stay hydrated throughout the day.

Medication Guide

Medication Leaflets & Helpful Resources

Download official patient information leaflets and additional guidance covering commonly prescribed ADHD medications, sleep hygiene, pregnancy advice and NICE guidance.

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